Plendil is a remedy is applied to treat elevated arterial pressure. Physicians also advise it in case of coronary heart disease, including the chronic one, and various types of angina. The drug can be used in patients with chronic heart failure and bronchial asthma, as well. Plendil is a commercial denomination of the chemical named Felodipine, which is essentially a calcium blocking agent. Here are the most commonly reported side effects from taking plendil.
Felodipine, just as any calcium blocking remedy, will most often be followed by mild headaches, swollen feet and palms and rushes of blood to different organs. These undesired effects are quite wide-spread and ought to pass after some time of intake.
Less common plendil felodipine side effects may vary from patient to patient and involve different organs and systems. The cardiovascular system may have the following negative manifestations: difficulty breathing, edema in legs, hyperemia in the upper part of the face, pulmonary embolism, chest pain, low arterial pressure, migraines, arrhythmia, uneven heart rhythm. Thrombocytopenia and hyperglycemia are some of the possible issues as well.
The negative effects for the central nervous system may include: dizziness, high level of tiredness, headaches, sleep/wake cycle imbalance, cramps, tremor, asthenia, fainting, paresthesia, nervousness, depression, increased anxiety, apathy, amnesia.
On the part of gastrointestinal tract, individuals may experience pain in the epigastric region, nausea, vomiting; changes in the activity of hepatic enzymes, increased bilirubin levels, dry mouth, stool disorders, flatulence, increased appetite, gastritis, pancreatitis. There are other rarely occurring long term side effects of plendil, like urination problems, sexual dysfunction, possibly development of joint pathologies, myasthenia; dermatitis, itching of the skin, urticaria, erythematous rash.
Vision may also be impaired (including disturbances in distance vision, pain in the eyes, diplopia, conjunctivitis), tinnitus, fever, nasal bleeding, abundant sweating.
Studies on the safety of the use of the drug during pregnancy were not conducted, so the administration of the drug is possible only under strict control of the attending physician in case the expected benefit for the mother is higher than the possible risks for the fetus. If it is necessary to prescribe a drug during breastfeeding, it is necessary to resolve the issue of discontinuing breastfeeding for the period of intake.
In case of an overdose in patients, there is hypotension, tachycardia, excessive expansion of peripheral vessels. In case of overdose, gastric lavage, absorption of absorbent substances, symptomatic therapy including maintenance of cardiovascular functions are indicated. Constant monitoring of blood pressure, a change in the position of the patient’s body, so that the limbs are on some elevation, are advised. Apart from that, intravenous administration of calcium and dopamine preparations are prescribed. When overdosed with Felodipine, hemodialysis does not have any beneficial effect.