This pair of medicines – Plendil and Amlodipine – is applied in cases of elevated blood pressure. Amlodipine is a chemical ingredient that can be encountered under its commercial name Norvasc, while Plendil is the commercial designation for the chemical Felodipine. Amlodipine can also be sold under its very name in some of its generic forms. There are quite comparable in terms of modes of action and their effect on the organism.
Basically, these two anti-hypertension drugs have very similar effects. The two remedies essentially impede calcium from moving through its designated channels in the heart and vessel tissues. This relaxes vessels’ tissues and lets them stretch, relieving elevated tension in the blood stream. So, when it comes to felodipine mechanism of action, it is practically identical to amlodipine’s. They are both advised by physicians to individuals with high arterial pressure and various forms of angina.
Both remedies are sold in the doses of 2,5 milligrams, 5 milligrams or 10 milligrams. Some producers make the pills different in colors, so Plendil’s lower 2,5-milligram pills is typically yellow, and it gets darker to being red and brownish for pills with bigger doses. The course is typically started with the dose of 5 milligrams every morning, for either medicine. It is ingested either before or after a light breakfast, once every 24 hours. The pill ought not be chewed or broken before intake, as it can hinder its effect.
Amlodipine and plendil tablets have similar undesired effects. As the most frequent ones, headaches, blushing and limb swelling can be named. Very rarely, on the part of cardiovascular system and hematopoiesis system, an individual may experience shortness of breath, swelling of the extremities, hyperemia of the upper part of the face and body, pain in the chest, hypotension, migraine, cardiac rhythm disturbances. Thrombocytopenia, leukopenia, hyperglycemia are also possible occurrences. On the part of the central nervous system, the following may occur: dizziness, fatigue, headache, disturbance of sleep and wakefulness, convulsions, tremor, asthenia, loss of consciousness, paresthesia, nervousness, depression, increased anxiety, apathy, amnesia.
The two remedies have similar contraindications, like increased individual sensitivity to the components of the drug, arterial hypotension, cardiogenic shock, collapse, pregnancy and lactation. Individuals with chronic heart failure, diabetes mellitus, impaired lipid metabolism, impaired liver function, elderly patients and persons under 18 years of age ought to take them very carefully, or avoid them altogether.
So, how to choose: plendil or amlodipine? It would depend on your individual sensitivity to the side components of the pills you want to choose, as well as your general health state. It is advised that your doctor choose the best form for you based on your clinical data.